1. Inayat S*, Barchini J*, Chen H, Feng L, Liu X, Cang J. (2015) Neurons in the Most Superficial Lamina of the Mouse Superior Colliculus Are Highly Selective for Stimulus Direction. J Neurosci 35(20). (*: co-first authors)


  1. Chen H*, Zhao Y*, Liu M*, Feng L, Puyang Z, Yi J, Liang P, Zhang HF, Cang J, Troy JB, Liu X. (2015) Progressive degeneration of retinal and superior collicular functions in mice with sustained ocular hypertension. Invest Ophthalmol Vis Sci 56(3):1971-84. (*: co-first authors)


  1. Puyang Z, Chen H, Liu X. (2015) Subtype-dependent Morphological and Functional Degeneration of Retinal Ganglion Cells in Mouse Models of Experimental Glaucoma. Journal of Nature and Science 1(5):e103.


  1. Chen H, Liu X*, Tian N. (2014) Subtype-dependent postnatal development of direction- and orientation-selective retinal ganglion cells in mice. J Neurophysiol 112(9):2092-101. (*: corresponding author)


  1. Thomson BR, Heinen S, Jeansson M, Ghosh AK, Fatima A, Sung HK, Onay T, Chen H, Yamaguchi S, Economides AN, Flenniken A, Gale NW, Hong YK, Fawzi A, Liu X, Kume T, Quaggin SE. (2014) A lymphatic defect causes ocular hypertension and glaucoma in mice. J Clin Invest 124(10):4320-4.


  1. Sarnaik R, Chen H, Liu X, Cang J. (2014) Genetic disruption of the On visual pathway affects cortical orientation selectivity and contrast sensitivity in mice. J Neurophysiol 111(11):2276-86.


  1. Wang BS, Feng L, Liu M, Liu X, and Cang J. (2013) Environmental Enrichment Rescues Binocular Matching of Orientation Preference in Mice that Have a Precocious Critical Period. Neuron 80 (1):198-209.


  1. Zhao X, Chen H, Liu X, Cang J. (2013) Orientation-selective Responses in the Mouse Lateral Geniculate Nucleus. J Neurosci 33(31):12751-63.


  1. Feng L, Zhao Y, Yoshida M, Chen H, Yang JF, Kim TS, Cang J, Troy JB, Liu X. (2013) Sustained ocular hypertension induces dendritic degeneration of mouse retinal ganglion cells that depends on cell type and location. Invest Ophthalmol Vis Sci 54(2):1106-17.


  1. Feng L, Chen H, Suyeoka G, Liu X. (2013) A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects. Journal of Visualized Experiments. J Vis Exp 78:e50440, doi:10.3791/50440.


  1. Song W, Wei Q, Feng L, Sarthy V,  Jiao S, Liu X, and Zhang ZF. (2013) Multimodal photoacoustic ophthalmoscopy in mouse. J Biophotonics 6(6-7):505-12.


  1. Yoshida M*, Feng L*, Grimbert F, Rangarajan KV, Buggele W, Copenhagen DR, Cang J, and Liu X (2011) Overexpression of neurotrophin-3 stimulates a second wave of dopaminergic amacrine cell genesis after birth in the mouse retina.  J Neurosci 31(35):12663-73. (*: co-first authors)


  1. Rangarajan KV*, Lawhn-Heath CA*, Feng L, Kim TS, Cang J, and Liu X. (2011) Detection of visual deficits in aging DBA/2J mice by two behavioral assays. Curr Eye Res 36:481-91.


  1. Wang L, Sarnaik R, Rangarajan K, Liu X, and Cang J. (2010) Visual receptive field properties of neurons in the superficial superior colliculus of the mouse. J Neurosci 30(49):16573-84.


  1. Cantrell DR, Cang J, Troy JB, and Liu X. (2010) Non-centered spike-triggered covariance analysis reveals neurotrophin-3 as a developmental regulator of receptive field properties of ON-OFF retinal ganglion cells. PLoS Comput Biol 6(10):e1000967.


  1. Wang L, Rangarajan KV, Lawhn-Heath CA, Sarnaik R, Wang BS, Liu X, and Cang J. (2009) Direction-specific disruption of subcortical visual behavior and receptive fields in mice lacking the beta2 subunit of nicotinic acetylcholine receptor. J Neurosci 29(41):12909-18. 


  1. Liu X, Robinson ML, Schreiber AM, Wu V, LaVail MM, Cang J, and Copenhagen DR. (2009) Regulation of neonatal development of retinal ganglion cell dendrites by neurotrophin-3 overexpression. J Comp Neurol 514(5):449-58.


  1. Cang J, Niell CM, Liu X, Pfeiffenberger C, Feldheim DA, and Stryker MP. (2008) Selective disruption of one Cartesian axis of cortical maps and receptive fields by deficiency in ephrin-As and structured activity. Neuron 57(4):511-23.


  1. Liu X, Grishanin R, Tolwani RJ, Renteria R, Reichardt LF, and Copenhagen DR (2007) Brain-derived neurotrophic factor and TrkB modulate visual experience-dependent refinement of neuronal pathways in retina. J Neurosci 27(27):7256-6.


  1. Cang J, Renteria RC, Kaneko M, Liu X, Copenhagen DR, and Stryker MP. (2005) Development of precise maps in visual cortex requires patterned spontaneous activity in the retina. Neuron 48 (5):797-809.


  1. Liu X and Green CB. (2002) Circadian regulation of nocturnin transcription by phosphorylated CREB in Xenopus retinal photoreceptor cells. Mol Cell Biol 22:7501-7511.


  1. Liu X and Green CB. (2001) A novel promoter element, PCE II, directs photo-receptor-specific expression of nocturnin in Xenopus laevis. J Biol Chem 276:15146-15154.

Selected Papers:

Department of

Ophthalmology

Department of

Neurobiology