People - Melissa



Name: Melissa Chamberlin McDevitt
Title: Doctoral Candidate
Degree: BS Biology, University of Michigan
Research area: Behavioral neuroscience, neuroendocrinology
Program: Interdepartmental Biological Sciences (IBiS)
Department of Neurobiology and Physiology
Northwestern University
2205 Tech Drive
Evanston, IL 60208
Phone: (847) 491-5528
Email: m-chamberlin@northwestern.edu 


Research description:

My research primarily focuses on the molecular mechanisms of behavior. One of my projects has established a role for ATP-sensitive potassium channels in mediating sexual behavior. I have shown that testosterone regulates expression of channel subunits and that blockade of these channels, which regulate neuronal excitability, can restore sexual behavior in long-term castrated male rats. A second project examines the role of ERE-independent ERa signaling in male reproductive function, sexual & aggressive behaviors, and development of sexually dimorphic brain regions. Using mice that possess a nonclassical estrogen receptor knock-in (NERKI) mutation (ERa-/NERKI), I have shown that ERE-independent ERa signaling does not rescue male sexual behavior but restores normal testosterone secretion in the absence of classical, ERE-dependent mechanisms.














Dr. Jon E. Levine
Department of Neurobiology and Physiology -  Institute for Neuroscience – Center for Reproductive Science
Northwestern University
2205 Tech Drive, Evanston, IL 60208. Office Phone: 847-491-7180. Lab Phone 847-491-7949

E-Mail: jlevine@northwestern.edu

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